Honey bees use propolis to cover and protect their hive. It is a special concoction of resin and bee enzymes, and has been found to be have antibacterial and other properties that help a colony stay healthy and well. Small openings in a hive tend to be filled with the stuff, including the spaces between boxes, covers, and other aspects of the modern hive. This is one reason beekeepers love their hive tool, as it is often the only way to pry apart boxes or covers to gain access to the hive.
Propolis is also used in the winter to reduce the size of an entrance to keep wind and other insects out of the hive.
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